U.S., June 12 -- ClinicalTrials.gov registry received information related to the study (NCT07642505) titled 'L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction' on June 08.
Brief Summary: Erectile dysfunction is a common male sexual health problem that may affect quality of life and sexual relationships. Tadalafil 5 mg once daily is an established oral treatment for erectile dysfunction. L-citrulline is an oral nitric oxide pathway supplement that may improve erectile function by increasing L-arginine availability.
This randomized trial will compare three oral treatment regimens in men with mild to moderate erectile dysfunction: L-citrulline 1500 mg/day, tadalafil 5 mg/day, and the combination of L-citrulline 1500 mg/day...