Clinical Trial: IRE After Chemotherapy for Locally Advanced Pancreatic Cancer

U.S., Sept. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07799935) titled 'IRE After Chemotherapy for Locally Advanced Pancreatic Cancer' on Aug. 28.

Brief Summary: This is a prospective, randomized, controlled, exploratory Phase II clinical study. Approximately 60 eligible patients with locally advanced pancreatic cancer who have received three cycles of chemotherapy induction and have non-progressive disease will be enrolled. All patients must be considered unresectable by MDT review and must provide written informed consent. Participants will be randomized 2:1. Forty patients will undergo open IRE followed by continuation of the original chemotherapy regimen; twenty patients will continue the original t...