U.S., June 12 -- ClinicalTrials.gov registry received information related to the study (NCT07641608) titled 'Investigation of Chemical Stability and Sterility of Morphine in Intrathecal Pumps for Long-Term Pain Management' on June 01.
Brief Summary: Intrathecal drug delivery systems (IDDS) are effective for managing chronic pain by delivering medications directly into the cerebrospinal fluid. Morphine, a primary opioid used in these systems, must remain chemically stable and sterile over prolonged periods to ensure patient safety and therapeutic efficacy . Previous studies have evaluated morphine stability in vitro under simulated conditions , indicating minimal degradation in saline over time . However, there is limited real-world data re...