Clinical Trial: Investigating the Efficacy and Mechanisms of Individualized tACS Targeting Anhedonia in Late-Life Depression

U.S., June 11 -- ClinicalTrials.gov registry received information related to the study (NCT07637773) titled 'Investigating the Efficacy and Mechanisms of Individualized tACS Targeting Anhedonia in Late-Life Depression' on May 29.

Brief Summary: This project focuses on clinical translational research into personalized transcranial alternating current stimulation (tACS) for treating anhedonia in late-life depression (LLD). Key components include: (1) Optimizing individualized tACS treatment parameters through randomized, double-blind, controlled trials and establishing precise treatment protocols using deep learning algorithms; (2) Assessing the short-term (2 weeks) and long-term (3 months) efficacy of tACS on depressive symptoms and anhedon...