U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07521293) titled 'Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF' on April 03.

Brief Summary: This study was designed to investigate predictors of atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFpEF), with a particular focus on the potential relationship between venous congestion and intracranial pressure dynamics. Among HFpEF patients, those with AF exhibited significantly higher right atrial pressure (RAP), larger right atrial area, higher CHA₂DS₂-VA scores, and increased optic nerve sheath diameter (ONSD), a noninvasive surrogate marker of intracranial p...