U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07519486) titled 'Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC' on April 02.
Brief Summary: Malnutrition is highly prevalent in patients with upper gastrointestinal tumors, which may negatively impact treatment tolerance and anti-tumor immune responses. This study aims to evaluate the efficacy and safety of intensive enteral nutritional support in patients with locally advanced unresectable esophageal squamous cell carcinoma (ESCC) undergoing conversion therapy. Participants receiving PD-1 inhibitors combined with chemotherapy will be randomly assigned to either intensive nutritional support or standard ...