U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07849933) titled 'Innate-like and NK Signatures in Chronic-Treated HIV Infection INSTINCT-HIV' on Sept. 24.
Brief Summary: Infection with the human immunodeficiency virus (HIV) is a chronic condition requiring lifelong antiretroviral therapy (ART). Despite prolonged virological control under suppressive ART, HIV persists in the form of a stable viral reservoir known as the 'integrated' reservoir, mainly localised in CD4+ memory T cells, which constitutes the obstacle to a functional or sterilising cure of the infection. The immunological mechanisms involved in the control, stability or gradual depletion of this reservoir are still not fully understood...