Clinical Trial: Induction PD-1 Inhibitor and Chemotherapy Followed by Chemoradiotherapy in Unresectable or Inoperable HPV-negative LA-HNSCC

U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07776340) titled 'Induction PD-1 Inhibitor and Chemotherapy Followed by Chemoradiotherapy in Unresectable or Inoperable HPV-negative LA-HNSCC' on Aug. 16.

Brief Summary: The goal of this clinical trial is to evaluate if adding chemotherapy and immunotherapy as induction treatment prior to definitive chemoradiotherapy could improve the outcomes of locally advanced HPV-negative head and neck squamous cell that are not amenable to surgery. The study aims to answer:

1. Does this treatment improve the survival outcomes of participants?

2. How do the tumors of participants response to the treatment?

3. How is the safety of this treatment? Researchers wi...