U.S., March 17 -- ClinicalTrials.gov registry received information related to the study (NCT07473115) titled 'Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments' on Dec. 22, 2025.

Brief Summary: Both severe pain and opioid therapy are associated with negative effects. The experience of pain is common in the intensive care unit, but it is highly individual and difficult to assess, as patients are often unable to communicate. This especially applies to patients who are mechanically ventilated. Behavioral assessment tools can help to identify pain in this population, but do not register overdose of opioid therapy. The AlgiScan(R) delivers the Pupillary Pain Index (PPI),...