U.S., Feb. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07433049) titled 'Impact of Supplementation in Improving Metabolic Health Outcomes (ISMOS) Study' on Dec. 22, 2025.
Brief Summary: This study investigates the role of multivitamin and multimineral (MVM) supplementation in improving metabolic, musculoskeletal, and mental health among midlife Asian women aged 40-60 years, a critical period marked by hormonal and physiological transitions from pre- to post-menopause. Evidence from the GUSTO cohort in Singapore has shown that higher plasma levels of vitamins B6, B9, B12, and D are associated with better metabolic profiles, insulin sensitivity, and mental wellbeing, while deficiencies are linked to increa...