Clinical Trial: Immune Reponses to RSV B Challenge in Older Adults (A Controlled Human Infection Study With RSV in Older People-02)

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07713628) titled 'Immune Reponses to RSV B Challenge in Older Adults (A Controlled Human Infection Study With RSV in Older People-02)' on July 14.

Brief Summary: This is a human challenge sequential cohort study involving healthy, non-smoking older adults aged 65-75 years. We aim to enrol 20 participants. There will be a sentinel cohort of 6 participants at the beginning of the study (Group 1). If no pausing rules are met, the remaining 14 participants will be enrolled for a total of 20 enrolled participants (Group 2).

The study will consist of three main phases: (1) screening and baseline, (2) inoculation and quarantine, and (3) follow up.

All par...