U.S., May 16 -- ClinicalTrials.gov registry received information related to the study (NCT07590986) titled 'Identification of MPN-specific Antigens and Anti-MPN TCRs in Myeloproliferative Neoplasm' on May 08.
Brief Summary: The goal of this observational study is to learn how the immune system responds to myeloproliferative neoplasms (MPN) in adults with known or suspected MPN. Researchers also want to identify immune cells that could help develop future immune-based treatments for MPN.
The main questions it aims to answer are:
* Are there T cells in the bone marrow that can recognize MPN cells?
* Which targets (antigens) on MPN cells are recognized by these immune cells?
* Can researchers identify T cell receptors (TCRs) that may be u...