Clinical Trial: i-PRF and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.

U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07848035) titled 'i-PRF and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.' on Sept. 22.

Brief Summary: This randomized split-mouth clinical trial will evaluate whether adding locally injected vitamin C to injectable platelet-rich fibrin (i-PRF) and microneedling improves gingival tissue thickness and keratinized tissue width in women with a thin gingival phenotype in the lower front teeth region.

Each participant will receive i-PRF and microneedling on both sides of the lower anterior region. One side will additionally receive vitamin C, while the opposite side will receive normal saline as a placebo. The treatment wi...