U.S., Sept. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07814235) titled 'Human Sperm Cryopreservation as an Alternative to the Decline of Sperm Quality With Aging' on June 29.
Brief Summary: This observational study will evaluate whether sperm cryopreservation can help preserve sperm quality and molecular characteristics that may be affected by increasing paternal age. Men aged 18 years and older will provide a semen sample and a blood sample for laboratory analysis. Each semen sample will be divided into fresh, slow-frozen, and vitrified aliquots. The study will compare sperm quality (as assessed by computer-assisted sperm analysis), DNA methylation profiles, DNA fragmentation, sperm telomere length be...