U.S., May 9 -- ClinicalTrials.gov registry received information related to the study (NCT07576777) titled 'Hormonal and Microbiota Modulation After Endoscopic Sleeve Gastroplasty' on April 16.

Brief Summary: Obesity is a chronic disease with a rapidly increasing prevalence, expected to affect up to 25% of the French population by 2030, and is associated with significant morbidity, mortality, and healthcare burden. Bariatric surgery, including sleeve gastrectomy and gastric bypass, remains the standard treatment for severe obesity but is irreversible and carries procedural risks.

Less invasive alternatives have emerged, including pharmacological treatments (GLP-1 receptor agonists and multi-agonists) and endoscopic approaches such as endos...