Clinical Trial: HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide

U.S., Aug. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07760948) titled 'HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide' on Aug. 07.

Brief Summary: This randomized, double-blind, placebo-controlled trial will evaluate whether daily calcium beta-hydroxy-beta-methylbutyrate (calcium-HMB) plus vitamin D3 preserves muscle mass, physical function, and resting metabolism in adults aged 65 to 85 years with type 2 diabetes who are newly starting semaglutide as part of usual clinical care. Participants will receive calcium-HMB plus vitamin D3 or matching placebo for approximately 6 months. The primary outcome is change in appendicular lean mass measured by dual-energy X-ray absorptiome...