U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT07556328) titled 'Histomolecular Profiling in Small-Bowel Diseases' on April 20.
Brief Summary: This prospective cohort study aims to establish reliable histological reference values for normal small-bowel mucosa, improve histological diagnostic quality in celiac disease, and develop an advanced molecular profile for disease diagnosis and treatment response evaluation. The study will collect duodenal biopsies from three groups: healthy controls undergoing clinically indicated gastroscopy, patients referred for primary celiac disease diagnostics, and patients with small-bowel mucosal injury unresponsive to a gluten-free diet. Patients will undergo ro...