Clinical Trial: Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease

U.S., Aug. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07759466) titled 'Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease' on Aug. 07.

Brief Summary: Periodontal disease is a chronic inflammatory condition of the tooth-supporting tissues in which the host inflammatory response drives the destruction of alveolar bone and periodontal attachment. The Hippo signaling pathway is a conserved regulatory network that controls cell proliferation, apoptosis, and bone homeostasis, but its role in human periodontal disease remains unknown. This observational, case-control study compared the levels of Hippo signaling pathway proteins (YAP, TAZ, MST1, TEAD, LATS1, M...