U.S., March 5 -- ClinicalTrials.gov registry received information related to the study (NCT07450469) titled 'Field Study on Intravenous Iloprost for Treatment of Severe Frostbite at High Altitude' on Feb. 20.

Brief Summary: The goal of this observational study is to learn whether intravenous iloprost treatment for severe frostbite (grades 3-4) is feasible and safe when delivered in pre-hospital, remote high-altitude settings.

The main questions it aims to answer are:

* Is it feasible to initiate and deliver guideline-based intravenous iloprost for grade 3-4 frostbite at high altitude and what logistical barriers arise?

* Does field-based initiation of iloprost increase tissue preservation and reduce amputations (compared to historical c...