U.S., Sept. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07812974) titled 'Extracellular Vesicle-based Strategy to Stratify Islets and Improve Their FItness Before Transplantation' on Aug. 31.
Brief Summary: Islet transplantation restores glucose tolerance in people living with diabetes characterised by high glycaemic variability: 90 per cent of patients were free from severe hypoglycaemia at 5 years, compared with 26 per cent prior to transplantation, and 50 per cent of patients were insulin-independent at 1 year. However, follow-up of participants is characterised by a gradual loss of islet function, with only 30 per cent of patients remaining insulin-independent at 5 years.
The greatest limitation and...