U.S., March 24 -- ClinicalTrials.gov registry received information related to the study (NCT07487077) titled 'Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya' on March 04.
Brief Summary: Background: Despite efforts to control cholera, outbreaks continue to occur in Kenya. Oral cholera vaccines (OCVs) are a critical tool in cholera prevention strategies. This study evaluates the immunogenicity of extended dosing intervals for Euvichol-S, a WHO-prequalified OCV, in a Phase IV non-inferiority trial.
Overview Design: This trial is a parallel-group, open-label, randomized, non-inferiority study. It aims to compare the immune response of three dosing schedules of the Euvichol-S OCV: a standard 2-week interval, a 2-month interval...