U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07774572) titled 'Exploration of Circular RNA in B-cell Hematologic Malignancies' on May 12.
Brief Summary: This is an investigator-initiated, open-label, single-arm, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics (PD), and preliminary efficacy of an in vivo circular RNA chimeric antigen receptor T cell in adult participants with R/R B-cell malignancies.
Study Start Date: May 26
Study Type: INTERVENTIONAL
Condition:
Lymphoma, B-Cell Refractory
Intervention:
DRUG: Investigational product (IP)
In Vivo Circular RNA Chimeric Antigen Receptor (CAR) T Cell Therapy
Recruitment Status: RECRUITI...