U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07711834) titled 'Exercise and PPARGC1A rs8192678 in Older Adults With Type 2 Diabetes and Cognitive Impairment' on July 07.
Brief Summary: This completed single-arm interventional study evaluated changes in metabolic control, cognitive function, and health-related physical fitness following a 12-week combined aerobic and resistance exercise program in older adults with type 2 diabetes mellitus and cognitive impairment. The study also explored whether the magnitude of response to exercise differed according to PPARGC1A rs8192678 genotype.
A total of 75 participants were genotyped, and 45 participants were included in a balanced genotype-stratified c...