U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07904221) titled 'Evaluation of the Antibacterial Effect of Probiotics on Cariogenic Bacteria in Children' on July 29, 2025.
Brief Summary: This randomized controlled clinical trial aims to evaluate the effect of oral probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei on cariogenic bacteria (Streptococcus mutans, Lactobacillus acidophilus) , salivary pH, buffering capacity, and plaque accumulation in children aged 6-12 years at high caries risk. Sixty children will be assigned into three groups: probiotic, positive control (xylitol lozenges), and negative control (no lozenges). Salivary and plaq...