U.S., Feb. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07426432) titled 'Evaluate the Effect of Fluoride-Releasing Composite Resin on Prevention of White Spot Lesions During Clear Aligner Therapy' on Dec. 20, 2025.

Brief Summary: Aim of this study: evaluate the effect of fluoride-releasing composite resin as attachments on prevention of white spot lesions.

Material and methods:

Type: Prospective, randomized split mouth controlled study.

Interventions:

Intervention Group (Experimental Side):

*Application of fluoride-releasing composite

Control Group (Control Side):

*Application of conventional composite

Outcome Measures:

Primary Outcome: Incidence and Severity of White Spot Lesions

Secondary Out...