Clinical Trial: ERCG vs Intensive Lifestyle Intervention for Weight Regain After GLP-1 RA Discontinuation

U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07908823) titled 'ERCG vs Intensive Lifestyle Intervention for Weight Regain After GLP-1 RA Discontinuation' on Sept. 30.

Brief Summary: This randomized controlled trial aims to evaluate the efficacy and safety of Endoscopic Radial Compression Gastroplasty (ERCG) in mitigating weight regain following discontinuation of glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Approximately 60 adults with prior GLP-1 RA use and confirmed weight rebound after treatment cessation will be randomized 1:1 to either ERCG combined with Intensive Lifestyle Intervention (ILI), or ILI alone.

The primary outcome is the between-group difference in percent Total Body...