U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07914790) titled 'Epidural Hydroxyethyl Starch for Post-Dural Puncture Headache in Parturients' on Oct. 29.
Brief Summary: The incidence of accidental dural puncture (ADP) among parturients receiving neuraxial labor analgesia has been reported to range from 1% to 1.5%. Post-dural puncture headache (PDPH) is a headache caused by low cerebrospinal fluid pressure resulting from substantial cerebrospinal fluid leakage after dural and arachnoid puncture. Epidural filling with hydroxyethyl starch (HES) via an epidural catheter has been used to prevent PDPH in patients with ADP. This multicenter prospective cohort study aimed to evaluate the effect of epidur...