Clinical Trial: Endoscopic Skin-Sparing vs. Conventional Mastectomy for Wound Complications in BC

U.S., April 24 -- ClinicalTrials.gov registry received information related to the study (NCT07548762) titled 'Endoscopic Skin-Sparing vs. Conventional Mastectomy for Wound Complications in BC' on Feb. 03.

Brief Summary: This randomized, open-label study compares endoscopic skin-sparing mastectomy (E-SSM) with conventional mastectomy (CM) in female patients with unilateral invasive breast cancer (T1-4aN0-3M0). The primary objective is to evaluate differences in postoperative wound complications and patient satisfaction, with secondary outcomes including breast appearance and oncological safety.

Eligible patients have a breast volume ≤ cup C and no/mild ptosis (grade I-II). A total of 258 participants (129 per group) will be enrolled ...