U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07753967) titled 'Efficacy of Chloroquine-Primaquine Treatment for Uncomplicated Plasmodium Vivax Malaria' on July 29.
Brief Summary: The study was designed to evaluate the current efficacy of this combination therapy against P. vivax, given the possibility of misuse or inadequate adherence to the regimen due to its lengthy treatment duration, in one of a vivax-endemic area in southwest Ethiopia. A 42-day in vivo drug efficacy study was carried out as an open, two arm clinical trial involving 192 patients with uncomplicated P. vivax mono infection. Participants were allocated into two groups: supervised (n = 96) and unsupervised (n = 96). Both groups...