Clinical Trial: Efficacy Comparison of DExamethasone Intravitreal Implant Combined With Aflibercept Versus Aflibercept Monotherapy in Treatment-naive Inflammatory Diabetic Macular Edema Patients

U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07438119) titled 'Efficacy Comparison of DExamethasone Intravitreal Implant Combined With Aflibercept Versus Aflibercept Monotherapy in Treatment-naive Inflammatory Diabetic Macular Edema Patients' on Feb. 06.

Brief Summary: This is a 12-month, prospective, randomized controlled, multi-center, open-label, superiority designed study. Treatment-Naive DME patient with inflammatory biomarkers, who meet the inclusion and exclusion criteria, will be recruited.

This study aims to provide the first direct comparative evidence within a Chinese cohort, evaluating the efficacy and safety of a combined DEX-I plus aflibercept therapy versus aflibercept monothera...