U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07476625) titled 'Efficacy and Safety of Thalidomide for Pediatric PFAPA Syndrome' on March 09.

Brief Summary: The goal of this clinical trial is to evaluate the efficacy and safety of thalidomide in the treatment of children with Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) syndrome. The study focuses on children diagnosed with PFAPA syndrome. The main questions it aims to answer are:

Can thalidomide significantly reduce the frequency of febrile episodes in children with PFAPA syndrome? What is the safety profile and tolerability of thalidomide in this pediatric population? Researchers will compare the thalidomide group t...