U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07539883) titled 'Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study' on March 25.
Brief Summary: This study aims to evaluate the clinical effectiveness of the oXiris(R) hemofilter in patients with septic shock and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). While some studies suggest that oXiris(R) may improve hemodynamic stability by removing endotoxins and cytokines, its impact on survival remains inconsistent.To provide more reliable causal evidence, this multicenter retrospective cohort study utilizes a Target Trial Emulation (TTE) approach. The study will compare patie...