U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07491627) titled 'Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment' on April 11, 2025.

Brief Summary: Impact of nicotine gingival intoxication on the clinical outcomes after periodontitis non surgical treatment

Study Start Date: Jan. 06, 2025

Study Type: INTERVENTIONAL

Condition: Periodontitis Smoking Cessation Tobacco Dependence

Intervention: PROCEDURE: periodontal non-surgical treatment

The procedure will consist of non-surgical periodontal treatment (NSPT), consisting of the removal of supra- and subgingival plaque using ultrasonic instruments.

Prior to the NSPT, all unstimulated saliva will be ...