Clinical Trial: ED90 of Tegileridine Combined With Propofol for LMA Insertion

U.S., June 25 -- ClinicalTrials.gov registry received information related to the study (NCT07665151) titled 'ED90 of Tegileridine Combined With Propofol for LMA Insertion' on June 18.

Brief Summary: This is a prospective two-group dose-finding trial using biased-coin sequential up-and-down design. We plan to enroll 108 patients who need general anesthesia with laryngeal mask airway placement, divided into young group (18-65 years old) and elderly group (65 years old and older). All patients will receive tegileridine combined with fixed-dose propofol for anesthesia induction. The main goal is to find the 90% effective dose (ED90) of tegileridine that can fully block body movement, cough, tearing and unstable blood pressure/heart rate during...