U.S., March 13 -- ClinicalTrials.gov registry received information related to the study (NCT07467603) titled 'ED50 of Remimazolam for Anesthesia Induction in Frail Elderly Patients' on March 01.
Brief Summary: This study aimed to determine the median effective dose (ED50) of remimazolam for loss of consciousness (LOC) in elderly and frail elderly patients using the Dixon up-and-down method, while utilizing a novel Respiratory Volume Monitor (RVM) to detect subclinical respiratory depression.
Study Start Date: Feb. 01, 2025
Study Type: INTERVENTIONAL
Condition:
Frailty
Anesthesia Induction
Intervention:
DRUG: Remimazolam Tosilate
The initial induction dose was set at 0.15 mg/kg administered as a single intravenous bolus over 30 secon...