U.S., July 16 -- ClinicalTrials.gov registry received information related to the study (NCT07704242) titled 'Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery' on July 09.
Brief Summary: This prospective observational study aims to evaluate early subclinical acute kidney injury associated with pneumoperitoneum and Trendelenburg positioning during gynecological laparoscopic surgery. Urinary neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) levels will be measured and normalized to urinary creatinine. Biomarker changes will be compared between patients undergoing surgery in 30deg and 45deg Trendelenburg positions. The study seeks to determine whether these biomarkers can detect early rena...