U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07424976) titled 'Early Detection of Brain Injury After Congenital Heart Surgery in Infants' on Feb. 13.
Brief Summary: Infants with congenital heart disease undergoing cardiac surgery with extracorporeal circulation are at risk for perioperative hypoxic-ischaemic brain injury. This prospective, single-centre observational cohort study will evaluate perioperative dynamics of serum biomarkers of neuronal, glial, and axonal injury and relate biomarker patterns to postoperative EEG changes and brain MRI findings, aiming to improve early detection of brain injury and identify children at higher risk of hypoxic encephalopathy.
Study Start Date: May 03, 2...