U.S., Sept. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07824193) titled 'Drug-drug Interaction Study of Clemizole (EPX-100) in Healthy Participants' on Sept. 11.
Brief Summary: This is a 3-part, drug-drug interaction study in healthy participants. Each part is designed as a 2-period, fixed-sequence and can be conducted concurrently.
Part 1 will assess the effect of itraconazole on the pharmacokinetics (PK) of EPX-100. Part 2 will assess the effect of phenytoin on the PK of EPX-100. Part 3 will assess the effect of EPX-100 on the PK of omeprazole, midazolam, and bupropion.
Study Start Date: Jan. 15, 2025
Study Type: INTERVENTIONAL
Condition:
Drug Drug Interaction
Intervention:
DRUG: EPX-100
Oral ...