Clinical Trial: Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation?

U.S., March 17 -- ClinicalTrials.gov registry received information related to the study (NCT07472244) titled 'Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation?' on March 04.

Brief Summary: Eccentric exercise, particularly when novel and strenuous, can cause soreness and inflammation, impairing subsequent exercise performance. These performance decrements are attributable to oxidative stress and inflammation. Interestingly, a single bout of eccentric exercise can confer protective effects, ameliorating the negative consequences in subsequent bouts. This is termed the repeated bout effect (RBE), which would be of interest to athletes considering the detrimental effects of strenuous eccentric exerci...