U.S., June 17 -- ClinicalTrials.gov registry received information related to the study (NCT07651397) titled 'Dietary Modulation of Urinary MCP-1 in ADPKD' on June 09.
Brief Summary: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst growth and declining kidney function. Inflammatory pathways, including those mediated by monocyte chemoattractant protein-1 (MCP-1), are increasingly recognized as contributors to disease progression. Metabolic alterations in cystic epithelial cells may influence inflammatory signaling, suggesting a potential role for dietary interventions targeting metabolic pathways.
This study is a prospective, randomized, open-label crossover trial designed to evaluate the effect of a...