U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07603427) titled 'Development of Biofunctional 3D-Printed Orthodontic Aligners With Antimicrobial and Remineralizing Properties' on April 24.
Brief Summary: Clear orthodontic aligners are widely used due to their esthetics and patient comfort; however, prolonged wear may promote biofilm accumulation and enamel demineralization. This laboratory-based (in vitro) study aims to develop and evaluate a novel directly 3D-printed orthodontic aligner resin modified with antimicrobial and remineralizing agents.
The study will investigate the incorporation of dimethylaminohexadecyl methacrylate (DMAHDM) as an antibacterial agent and amorphous calcium phosphate ...