U.S., Sept. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07816744) titled 'Danish Trial of Weight Loss to Reduce Atrial Fibrillation Progression' on Sept. 08.
Brief Summary: Obesity is an important risk factor for the development and progression of atrial fibrillation. Sustainable weight loss likely reduces the burden of atrial fibrillation, which has yet to be proven in adequately sized randomised trials.
In a national, multicentre randomised trial we will test, whether a sustainable weight loss of more than 10% reduces atrial fibrillation progression and burden in patients with symptomatic paroxysmal or early persistent atrial fibrillation and a body mass index >=27 kg/m2. A total of 480 patients will ...