Clinical Trial: Cousin vs. Sibling Donors in Haplo-HSCT

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07662382) titled 'Cousin vs. Sibling Donors in Haplo-HSCT' on June 16.

Brief Summary: This observational study aims to emulate a hypothetical pragmatic, multicenter, non-blinded clinical trial enrolling adult patients undergoing haploidentical hematopoietic stem cell transplantation (haplo-HSCT) with grafts derived from either cousin or sibiling donors.

The main research question is whether cousin donor-derived haplo-HSCT is associated with inferior clinical outcomes relative to sibling donor-derived haplo-HSCT.

Study participants consist of adult patients diagnosed with hematological malignancies who underwent cousin or sibiling haplo-HSCT between...