U.S., March 21 -- ClinicalTrials.gov registry received information related to the study (NCT07485985) titled 'Coronary Sinus Reducer Therapy for Persisting Angina' on March 12.
Brief Summary: Refractory angina due to advanced obstructive coronary artery disease (CAD) remains a major clinical problem with limited evidence-based treatment options. The coronary sinus reducer (CSR) is an hourglass-shaped stainless-steel mesh device designed to create a controlled narrowing of the coronary sinus (CS). By increasing CS pressure, CSR implantation may improve myocardial perfusion and reduce anginal symptoms, although the physiological mechanisms underlying this effect remain incompletely understood.
REDUCE-ANGINA is a prospective observational st...