Clinical Trial: Comparison of Lateral Internal Sphincterotomy Techniques for Chronic Anal Fissure

U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07520552) titled 'Comparison of Lateral Internal Sphincterotomy Techniques for Chronic Anal Fissure' on April 03.

Brief Summary: This prospective randomized controlled trial compares three lateral internal sphincterotomy (LIS) techniques in patients with chronic anal fissure refractory to medical treatment: (1) Spasm-Controlled LIS (serial small sphincterotomies using an anal calibrator until 30 mm anal caliber is achieved, under local anesthesia plus sedation), (2) LIS up to the Fissure Apex (spinal or general anesthesia), and (3) LIS up to the Dentate Line (spinal or general anesthesia). The primary outcomes are fissure healing rate and fecal inco...