Clinical Trial: Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis.

U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT07451847) titled 'Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis.' on Nov. 17, 2025.

Brief Summary: The PREP-ANCA study seeks to establish a more personalized treatment strategy for ANCA-associated vasculitides by assessing the efficacy of pre-emptive rituximab administration upon ANCA repositivity in preventing relapses in granulomatosis with polyangiitis and microscopic polyangiitis.

Study Start Date: Feb., 2026

Study Type: INTERVENTIONAL

Condition: ANCA Associated Vasculitis (AAV) Polyangiitis (...