U.S., April 24 -- ClinicalTrials.gov registry received information related to the study (NCT07548918) titled 'Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo"' on April 16.
Brief Summary: This study is a randomized controlled trial comparing microneedling with topical minoxidil 5% versus microneedling with minoxidil combined with NB-UVB phototherapy in stable vitiligo.
It aims to evaluate both clinical and histopathological outcomes in 30 patients with non-segmental stable vitiligo.
Vitiligo is a chronic depigmenting disorder caused by melanocyte destruction with significant psychosocial impact.
The study also investigates immunohistochemical changes, particularly Wnt/β-catenin signalin...