U.S., July 30 -- ClinicalTrials.gov registry received information related to the study (NCT07732699) titled 'Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis)' on July 23.
Brief Summary: This study is being conducted at multiple hospitals and clinics to better understand whether antibiotics truly help children feel better when they have a sinus infection (acute sinusitis). Children in the study are randomly assigned (like flipping a coin) to receive either amoxicillin, amoxicillin-clavulanate, or a placebo (a look-alike medicine with no active antibiotic). Neither families nor study staff know which treatment the child is receiving during the study. The main goal is to compare how ...