Clinical Trial: Clinical Thresholds of Double-strand Breaks in Sperm's DNA in ART

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07621991) titled 'Clinical Thresholds of Double-strand Breaks in Sperm's DNA in ART' on May 27.

Brief Summary: The goal of this prospective observational study is to learn about the impact of double-strand sperm DNA fragmentation (dsSDF) on assisted reproductive technology (ART) outcomes and to derive clinically relevant threshold values for dsSDF and global sperm DNA fragmentation (SDF) in couples undergoing intracytoplasmic sperm injection (ICSI). The main questions it aims to answer are:

* Can clinically relevant threshold values of dsSDF and global SDF predict live birth rates following ICSI?

* Does elevated dsSDF reduce live birth rates followi...