Clinical Trial: Clinical Investigator-Initiated Trial (IIT) of PD-L1-Targeted Radionuclide Probes

U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07848243) titled 'Clinical Investigator-Initiated Trial (IIT) of PD-L1-Targeted Radionuclide Probes' on Sept. 18.

Brief Summary: [18F]F-PDL1-3 molecular probe was used to detect the expression of PD-L1 in primary and metastatic tumors of patients with solid tumors. The heterogeneity of PD-L1 expression in the same lesion and different lesions was further evaluated, and the changes of PD-L1 expression in the course of the disease were observed. This method is helpful for the screening of patients with solid tumors with high PD-L1 expression, efficacy monitoring, and early warning of drug resistance and/or recurrence or metastasis, and ultimately achi...